GPS2 Polyclonal Antibody

GPS2 Polyclonal Antibody

Catalog Number:
A001511738RED
Mfr. No.:
RD89587A
Price:
$416
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      • Overview
        • Calculated MW: 51kDa
          Observed MW: 55kDa

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          Background

          This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          A synthetic peptide of mouse GPS2
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.01% thiomersal,50% glycerol,pH7.3.
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1mg/mL
          Antigen
          GPS2, AMF-1 (Gene ID:56310)

          * For reference only.

      • Applications
        • Application
          WB; IP
        • Application Dilutions
          WB 1:500-1:2000
          IP 1:20-1:50

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