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GM1-Lysoganglioside sodium

GM1-Lysoganglioside sodium

Catalog Number:
C003144061BIO
Mfr. No.:
OL44867
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      • Overview

        • GM1-Lysoganglioside (sodium salt) has the core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with sialic acid linked α2,3 to the inner galactose residue and sphingosine linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GM1 lysoganglioside has been shown that it is capable of binding amyloid-β proteins and can act as a seed for amyloid fibril formation, in early stages of Alzheimer’s disease (Chiricozzi, 2020).

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      • Properties
        • Categories
          Ganglioside Oligosaccharides and Gangliosides
          Alternative Name
          lyso-Monosialoganglioside GM1;Lyso-GM1
          CAS Number
          94458-59-0
          Molecular Formula
          C55H97N3O30·xNa
          Molecular Weight
          1,280.36 g/mol
          Note
          There is no hazardous surcharge associated with this product.
          There is no special packaging charge associated with this product.

          * For research use only. Not for human or veterinary use

      • Reference

        • Ledeen et al (2009) Neurobiology Meets Glycosciences, In: The Sugar Code (Ed: Gabius H. J), pp 495-516, Wiley-VCH, Weinheim.
          Chiricozzi et al (2020) GM1 Ganglioside Is A Key Factor in Maintaining the Mammalian Neuronal Functions Avoiding Neurodegeneration, International Journal of Molecular Sciences, 21(3), 868.

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