FNDC3B Polyclonal Antibody

FNDC3B Polyclonal Antibody

Catalog Number:
A001507931RED
Mfr. No.:
RD252260A
Price:
$253
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      • Overview
        • Gene Accession: BC012204

          Please contact us at for specific academic pricing.

          Background

          Adipogenesis, the process of transforming pre-adipocytes into mature fat cells, is of particular interest due to the role adipocytes play in obesity and type II diabetes. Adipocytes have been shown to affect a variety of functions, including hemostasis, angiogenesis and energy balance, by secreting hormones and bioactive peptides. The FNDC3B protein, also designated FAD104 (factor for adipocyte differentiation 104) or HCV NS5A-binding protein 37, is expressed during early adipogenesis. Belonging to the FNDC3 family of proteins, FNDC3B is a 1,204 amino acid protein that contains nine fibronectin type-III domains. FNDC3B-deficient mice die within one day of birth, suggesting that FNDC3B is crucial for postpartum survival. Mouse embryonic fibroblasts (MEFs) with loss of FNDC3B function displayed a reduction in stress fiber formation, indicating a role for FNDC3B in cell proliferation, adhesion, spreading and migration.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Full length fusion protein
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          1.8 mg/mL
          Antigen
          DKFZp686D14170 , DKFZp762K137, Factor for adipocyte differentiation 104, FAD104, fibronectin type III domain containing 3B , FLJ23399, HCV NS5A binding protein 37 , MGC10002, NS5ABP37, PRO4979, YVTM2421 (UniProt:Q53EP0)

          * For reference only.

      • Applications
        • Application
          IHC; ELISA
        • Application Dilutions
          IHC 1:30-1:150
          ELISA 1:5000-1:10000

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