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Overview
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This antibody reacts with the CD103 antigen, which is strongly expressed on all the various subsets of human Intra-Epithelial Lymphocytes as well as 40% of T cells, 30% of mesenteric lymphoblasts and some lymphocytes in other mucosae. CD103 is belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. Treg cells express high level of CD103. Hairy cell leukemia has also been shown to express CD103.
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