Fibrinogen beta Chain Mouse Monoclonal Antibody

Fibrinogen beta Chain Mouse Monoclonal Antibody

Catalog Number:
A001450359ZEN
Mfr. No.:
Zen-220322
Price:
  • Size:
    100μl
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          Fibrinogen beta chain, also known as FGB, is a gene found in humans and most other vertebrates with a similar system of blood coagulation.It is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.

      • Properties
        • Host
          mouse
          Isotype
          IgG1
          Reactivity
          human
          Clone
          1F9
          Immunogen
          Purified recombinant fragment of human FGB expressed in E. Coli.
          Purification
          Ascitic Fluid
          Conjugate
          Unconjugated
          Formulation
          Ascitic fluid containing 0.03% sodium azide.
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Molecular Weight
          Calculated MW: 56 kDa; Observed MW: 52 kDa
          Antigen
          (Gene ID:2244; UniProt:P02675)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1/500-1/1000

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