FGR Polyclonal Antibody

FGR Polyclonal Antibody

Catalog Number:
A001507542RED
Mfr. No.:
RD219870A
Price:
$253
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      • Overview
        • Gene Accession: NP005239

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          Background

          This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Synthetic peptide of human FGR
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          2.04 mg/mL
          Antigen
          c fgr, c fgr protooncogene, c src 2 proto oncogene, c src2, Fgr, FGR, FLJ43153, Gardner Rasheed feline sarcoma viral (v fgr), Gardner Rasheed feline sarcoma viral (v fgr) oncogene homolog, Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, MGC75096, p55 c fgr protein, P55 FGR, P55-FGR, p55c fgr, p58-Fgr, p58c fgr, p58c-Fgr, Proto oncogene c Fgr, Proto oncogene tyrosine protein kinase FGR, Proto-oncogene c-Fgr, SRC 2, SRC2, Tyrosine protein kinase Fgr, Tyrosine-protein kinase Fgr (UniProt:P09769)

          * For reference only.

      • Applications
        • Application
          IHC; ELISA
        • Application Dilutions
          IHC 1:50-1:300
          ELISA 1:5000-1:10000

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