FGFR1OP Recombinant Protein

FGFR1OP Recombinant Protein

Catalog Number:
P001416473ABE
Mfr. No.:
Abe32-3007
Price:
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • FGFR1OP Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 403 amino acids (1-379 a.a) and having a molecular mass of 43.5kDa. FGFR1OP is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. FGFR1 oncogene partner (FGFR1OP) is a member of the FGFR1OP family. The FGFR1OP protein is an essentially hydrophilic protein proposed to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation, fusing the FGFR1OP gene and the FGFR1 gene, is seen in cases of myeloproliferative disorder. The ensuing chimeric protein contains the N-terminal leucine-rich region of the FGFR1OP protein fused to the catalytic domain of FGFR1. The FGFR1OP gene is believed to play a significant role in normal proliferation and differentiation of the erythroid lineage.

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      • Properties
        • Protein Name
          FGFR1 oncogene partner, FGFR1OP, FOP.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 85.0% as determined by SDS-PAGE.
          Formulation
          FGFR1OP protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 1mM DTT.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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