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Overview
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FDFT1 Human Recombinant produced in E. Coli is a single,non-glycosylated polypeptide chain containing 306 amino acids (1-283 a.a) andhaving a molecular mass of 35.4 kDa. FDFT1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Farnesyl-Diphosphate Farnesyltransferase 1, also known as FDFT1 is amembrane-associated enzyme sited at a branch point in the mevalonate pathway. FDFT1belongs to the phytoene/squalene synthase family. FDFT1 is the 1st specificenzyme in cholesterol biosynthesis, which catalyzes the dimerization of 2molecules of farnesyl diphosphate in a two-step reaction to form squalene.
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Overview