FDFT1 Recombinant Protein

FDFT1 Recombinant Protein

Catalog Number:
P001416556ABE
Mfr. No.:
Abe32-2321
Price:
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • FDFT1 Human Recombinant produced in E. Coli is a single,non-glycosylated polypeptide chain containing 306 amino acids (1-283 a.a) andhaving a molecular mass of 35.4 kDa. FDFT1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Farnesyl-Diphosphate Farnesyltransferase 1, also known as FDFT1 is amembrane-associated enzyme sited at a branch point in the mevalonate pathway. FDFT1belongs to the phytoene/squalene synthase family. FDFT1 is the 1st specificenzyme in cholesterol biosynthesis, which catalyzes the dimerization of 2molecules of farnesyl diphosphate in a two-step reaction to form squalene.

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      • Properties
        • Protein Name
          Farnesyl-Diphosphate Farnesyltransferase 1, SqualeneSynthase, SQS, SS, FPP:FPP Farnesyltransferase, EC 2.5.1.21, DGPT, ERG9, Presqualene-Di-DiphosphateSynthase, Squalene Synthetase, Farnesyl-Diphosphate, Farnesyltransferase, FDFT1.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 85.0% as determined by SDS-PAGE.
          Formulation
          FDFT1 protein solution (0.25 mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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