ErbB 2 Rabbit Polyclonal Antibody

ErbB 2 Rabbit Polyclonal Antibody

Catalog Number:
A001450236ZEN
Mfr. No.:
Zen-380836
Price:
  • Size:
    100μl
    Quantity:
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      • Overview
        • Please contact us at for specific academic pricing.

          Background

          This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase.

      • Properties
        • Host
          rabbit
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          A synthesized peptide derived from human ErbB2 (HER2)
          Purification
          Affinity Chromatography
          Conjugate
          Unconjugated
          Formulation
          Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Molecular Weight
          Calculated MW: 138 kDa; Observed MW: 185 kDa
          Antigen
          (Gene ID:2064; UniProt:P04626)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB; IHC-P; ICC/IF; IP; FC
        • Application Dilutions
          WB 1/500-1/1000
          IHC 1/50-1/100
          IF 1/50-1/200
          IP 1/20
          FC 1/50-1/100

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