eIF3 zeta Rabbit Polyclonal Antibody

eIF3 zeta Rabbit Polyclonal Antibody

Catalog Number:
A001450186ZEN
Mfr. No.:
Zen-370098
Price:
  • Size:
    100μl
    Quantity:
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      • Overview
        • Please contact us at for specific academic pricing.

          Background

          Translation initiation in eukaryotes necessitates the assembly of an 80S ribosomal complex containing methionyl initiator tRNA (Met-tRNAiMet), which is base paired at the initiation codon (AUG, GUG) in eligible transcripts. Eukaryotic initiation factors (eIFs) are utilized in a sequence of reactions that leads to 80S ribosomal assembly and initiation of translation. Eukaryotic initiation factor 3 (eIF3) is the largest family of eIFs and consists of at least 12 unique subunits in mammals. eIFε, also known as eIF p47, binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA and associates with the complex p170-eIF3.

      • Properties
        • Host
          rabbit
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Synthetic peptide corresponding to Human eIF3ζ.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
          Antigen
          (Gene ID:8664; UniProt:O15371)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB; IHC-P
        • Application Dilutions
          WB 1/500-1/1000
          IHC 1/50-1/200

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