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Overview
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EFNA3 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 217 amino acids (23-214 a.a) and having a molecular mass of 24kDa. EFNA3 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. EFNA3 belongs to the ephrin (EPH) family. The ephrins and EPH-related receptors include the largest subfamily of receptor protein-tyrosine kinases which have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Ephrins are divided into the ephrin-A (EFNA) class and the ephrin-B (EFNB) class, based on their structures and sequence relationships. The Ephrins from the EFNA class are anchored to the membrane by a glycosylphosphatidylinositol linkage, while the others from the EFNB class are transmembrane proteins.
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Overview