DYNLL1 cDNA

- Overview
  - DYNLL1, also known as DLC8 or PIN (protein inhibitor of neuronal nitric oxide synthase), has been identified as a protein that interacts with NOS1 resulting in NOS1 inhibition. Binding of this protein destabilizes NOS1 (Neuronal nitric oxide synthase) dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. DYNLL1 is a ubiquitously expressed protein that exhibits high expression in testis and moderate expression in brain.
    
    PRODUCT INFORMATION
    Antigen Species: Human
    NCBI Accession No: NP_001032583.1
    RNA Reference Number: NM_001037494.1
    OMIM Number: 601562
    Chromosome Location: 12q24.23
    cDNA size: 270bp
    Vector description: This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.
    
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- Properties
  - Protein Name
    
    DLC1, DLC8, DNCL1, DNCLC1, hdlc1, LC8, LC8a, PIN
    
    Type
    
    cDNAs
    
    Formulation
    
    Lyophilized
    
    Storage
    
    Store the plasmid at -20°C.
    
    Sequence
    
    Nucleotide Sequence: ATGTGCGACC GAAAGGCCGT GATCAAAAAT GCGGACATGT CGGAAGAGAT GCAACAGGAC TCGGTGGAGT GCGCTACTCA GGCGCTGGAG AAATACAACA TAGAGAAGGA CATTGCGGCT CATATCAAGA AGGAATTTGA CAAGAAGTAC AATCCCACCT GGCATTGCAT CGTGGGGAGG AACTTCGGTA GTTATGTGAC ACATGAAACC AAACACTTCA TCTACTTCTA CCTGGGCCAA GTGGCCATTC TTCTGTTCAA ATCTGGTTAA
    Translation Sequence: MCDRKAVIKN ADMSEEMQQD SVECATQALE KYNIEKDIAA HIKKEFDKKY NPTWHCIVGR NFGSYVTHET KHFIYFYLGQ VAILLFKSG.
    
    * For research use only. Not intended for human, diagnostics or veterinary use.
- Applications
  - Application Description
    
    (1) Centrifuge at 7000rpm for 1 minute. (2) Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid.

DYNLL1 cDNA

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