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Overview
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DR1, also known as NC2-beta, is a TBP (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. By selectively repressing polymerases II and III, DR1 may shift the physiological balance of transcriptional output in favor of polymerase I.
PRODUCT INFORMATION
Antigen Species: Human
NCBI Accession No: NP_001929.1
RNA Reference Number: NM_001938.2
OMIM Number: 601482
Chromosome Location: 1p22.1
cDNA size: 531bp
Vector description: This shuttle vector contains the complete ORF. It is inseted Nde I to BamH I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.Please contact us at for specific academic pricing.
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Overview