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Overview
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DNAL1 Human Recombinant produced in E. coli is a single polypeptide chain containing 213 amino acids (1-190) and having a molecular mass of 23.9 kDa. DNAL1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Dynein Axonemal Light Chain 1 (DNAL1) functions as a component of the outer dynein arms complex. DNAL1 acts as the molecular motor which supplies the force to move cilia in an ATP-dependent manner. DNAL1 is expressed in tissues with motile cilia or flagella and takes part in the movement of sperm flagella. Alternate splicing results in numerous transcript variants.
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Overview