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Overview
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DCK is a key enzyme in the salvage of deoxyribonucleosides and in the activation of clinically relevant nucleoside analogues. This protein is responsible for the 5'-phosphorylation of purine and pyrimidine deoxynucleosides to the corresponding monophosphates using ATP or uTP as phosphate donors. Deficiency of this enzyme activity is associated with resistance to antiviral and anticancer chemotherapeutic agents, whereas increased enzyme activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives.
PRODUCT INFORMATION
Antigen Species: Human
NCBI Accession No: NP_000779.1
RNA Reference Number: NM_000788.2
OMIM Number: 125450
Chromosome Location: 4q13.3-q21.1
cDNA size: 783bp
Vector description: This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.Please contact us at for specific academic pricing.
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Overview