Cytosolic Phospholipase A2 Rabbit Polyclonal Antibody

Cytosolic Phospholipase A2 Rabbit Polyclonal Antibody

Catalog Number:
A001449639ZEN
Mfr. No.:
Zen-822144
Price:
  • Size:
    100μl
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      • Overview
        • Please contact us at for specific academic pricing.

          Background

          This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.

      • Properties
        • Host
          rabbit
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Fusion protein of human PLA2G4A
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Molecular Weight
          Calculated MW: 85 kDa; Observed MW: 85 kDa
          Antigen
          (Gene ID:5321; UniProt:P47712)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB; IHC-P
        • Application Dilutions
          WB 1/500-1/1000
          IHC 1/50-1/100

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