CyFlow™ CD271 Purified

CyFlow™ CD271 Purified

Catalog Number:
A001343474SYS
Mfr. No.:
AV732768
Price:
$306
  • Size:
    0.1 mg (0.1 mL)
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          CD271 (NGFR, p75NGFR, p75NTR) is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.

      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG1
          Reactivity
          cat; ferret; human; non-human primates; rabbit
          Clone
          NGFR5
          Immunogen
          Purified CD271 protein isolated from human melanoma cell line A875
          Conjugate
          Purified
          Formulation
          The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
          Storage
          Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
          Concentration
          1 mg/mL
          Regulatory Status
          RUO
          Antigen
          LNGFR, NGFr(p75) , NTR, p75(NTR), TNFRSF16

          * Research use only

      • Applications
        • Application
          Flow Cytometry; Immunocytochemistry; IHC (paraffin); Immunoprecipitation; WB

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