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Overview
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Background
CD261 (TRAIL-R1; TRAIL receptor 1 or DR4) is a type I transmembrane protein. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF κB activation in many cells and tissues.
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- Properties
- Applications
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Overview