CyFlow™ CD26 APC

CyFlow™ CD26 APC

Catalog Number:
A001343447SYS
Mfr. No.:
AP029195
Price:
$488
  • Size:
    100 tests (1.0 mL)
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          CD26 (DPP-IV; dipeptidyl peptidase IV) is a homodimeric cell surface serine peptidase that degradates IFN-γ-induced cytokines, acts as a T cell costimulatory molecule, and participates in multiple immunopathological roles in leukocyte homing and inflammation. Alterations in its peptidase activity are characteristic of malignant transformation. The enzymatic activity increases dramatically with tumor grade and severity. CD26 is expressed in various blood cell types, but also e.g. in cells that are histogenetically related to activated fibroblasts. Alterations in CD26 density have been reported on circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.

      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG2a
          Reactivity
          human
          Clone
          BA5b
          Immunogen
          A human T cell clone
          Conjugate
          APC
          Formulation
          The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
          Storage
          Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
          Regulatory Status
          RUO
          Antigen
          ADABP , ADCP2, CD26, DPPIV, TP103

          * Research use only

      • Applications
        • Application
          Flow Cytometry
          Application Description
          The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

          Emission Maximum: 660 nm
          Excitation Maximum: 650 nm

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