Name: CyFlow™ CD195 PE
Price: 488.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    CD195 (CCR5, CKR-5) is a receptor for inflammatory CC-chemokines (characterized by a pair of adjacent cysteine residues), such as MIP-1 α, MIP-1 β, or RANTES. It is a G protein-associated seven-pass transmembrane protein expressed on resting T cells with memory/effector phenotype, monocytes, macrophages and immature dendritic cells. This chemokine receptor regulates the activation and directed migration of leukocytes. Importantly, along with CD4, CD195 functions as a major receptor for HIV. Their ligand is the viral glycoprotein gp120.
- Properties
  - Host
    
    mouse
    
    Antibody Type
    
    monoclonal
    
    Isotype
    
    IgG1
    
    Reactivity
    
    human
    
    Clone
    
    T21/8
    
    Immunogen
    
    CCR5 peptide (Met1-Lys22) KLH conjugate
    
    Conjugate
    
    PE
    
    Formulation
    
    The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
    
    Storage
    
    Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
    
    Regulatory Status
    
    RUO
    
    Antigen
    
    CC-CKR5, CCR5 , CKR5, CMKBR5
    
    * Research use only
- Applications
  - Application
    
    Flow Cytometry
    
    Application Description
    
    The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    
    Emission Maximum: 576 nm
    Excitation Maximum: 496 nm, 565 nm