Name: CyFlow™ CD108 FITC
Price: 456.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    CD108 (SEMA7A; Semaphorin 7A) is a GPI-anchored semaphorin family member, which enhances central and peripheral axonal growth and is required for proper axon track formation during ebryogenesis. CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in immune system affects cell proliferation, chemotaxis and cytokine release. On erythrocytes CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signalizes through its receptors - plexin C1 and β1 integrins.
- Properties
  - Host
    
    mouse
    
    Antibody Type
    
    monoclonal
    
    Isotype
    
    IgM
    
    Reactivity
    
    human
    
    Clone
    
    MEM-150
    
    Immunogen
    
    Human Acute Lymphocytic Leukemia (ALL) T cells
    
    Conjugate
    
    FITC
    
    Formulation
    
    The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
    
    Storage
    
    Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
    
    Regulatory Status
    
    RUO
    
    Antigen
    
    GPI-gp80, JMH, SEMA7A , Sema K1
    
    * Research use only
- Applications
  - Application
    
    Flow Cytometry
    
    Application Description
    
    The reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 20·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
    
    Emission Maximum: 518 nm
    Excitation Maximum: 490 to 495 nm