Cyclooxygenase 2 Mouse Monoclonal Antibody

Cyclooxygenase 2 Mouse Monoclonal Antibody

Catalog Number:
A001449498ZEN
Mfr. No.:
Zen-222215
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      • Overview
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          Background

          Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.

      • Properties
        • Host
          mouse
          Isotype
          Mouse IgG1
          Reactivity
          human
          Immunogen
          Purified recombinant fragment of human PTGS2 expressed in E. Coli.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Purified antibody in PBS with 0.05% sodium azide
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Antigen
          (Gene ID:5743; UniProt:P35354)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          ICC/IF; FC; ELISA
        • Application Dilutions
          IF 1/50-1/200
          FC 1/50-1/100
          ELISA 1/10000

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