Name: CRYGS Polyclonal Antibody (0.8 mg/mL) for WB, ELISA
Price: 253.00 USD

Overview
- Calculated MW: 21 kDa
  Observed MW: Refer to figures
  Gene Accession: BC069478
  
  Please contact us at for specific academic pricing.
  
  Background
  
  Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. This gene encodes a protein initially considered to be a beta-crystallin but the encoded protein is monomeric and has greater sequence similarity to other gamma-crystallins. This gene encodes the most significant gamma-crystallin in adult eye lens tissue. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Full length fusion protein
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  0.8 mg/mL
  
  Antigen
  
  AI327013, Beta-crystallin S, CRBS, CRYG8, crygs, Crystallin, gamma 8, Crystallin, gamma polypeptide 8, Crystallin, gamma S, CTRCT20, Gamma crystallin S, Gamma S crystallin, Gamma-crystallin S, Gamma-S-crystallin, Opacity due to poor secondary fiber cell junction; recessive nuclear cataract, Opj, rncat (UniProt:P22914)
  
  * For reference only.

Applications

Application

WB; ELISA

Application	Dilutions
WB	1:500-1:2000
ELISA	1:5000-1:10000

CRYGS Polyclonal Antibody (0.8 mg/mL) for WB, ELISA

CRYGS Polyclonal Antibody (0.8 mg/mL) for WB, ELISA

Background

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