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Overview
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CPEB1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 584 amino acids (1-561) and having a molecular mass of 64.5 kDa. CPEB1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) belongs to the cytoplasmic polyadenylation element (CPE) binding protein family, whose members regulate translation of cyclin B1 during embryonic cell divisions. The CPEB1 is a highly conserved protein which binds to a specific RNA sequence called the CPE found in the 3' UTR of some mRNAs. Analogous proteins in Xenopus and mouse function to stimulate cytoplasmic polyadenylation of dormant mRNAs with short polyA tails, resulting in their translation.
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Overview