CHCHD3 Recombinant Protein

CHCHD3 Recombinant Protein

Catalog Number:
P001415595ABE
Mfr. No.:
Abe32-3520
Price:
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • CHCHD3 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 250 amino acids (1-227 a.a) and having a molecular mass of 28.5kDa. CHCHD3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Coiled-coil-helix-coiled-coil-helix domain containing 3 (CHCHD3), is a protein-coding gene. CHCHD3 is essential for maintenance of mitochondrial crista integrity and mitochondrial function. In addition, CHCHD3 may perform as a scaffolding protein that stabilizes protein complexes involved in crista architecture and protein import. CHCHD3 may also act as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. Lung cancer has been associated with CHCHD3.

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      • Properties
        • Protein Name
          Regulatory Subunit 22, MINOS3, PPP1R22, MitochondrialInner Membrane Organizing System 3, Protein Phosphatase 1, Coiled-Coil-Helix-Coiled-Coil-HelixDomain-Containing Protein 3 Mitochondrial, Protein Phosphatase 1, RegulatorySubunit 22.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 80.0% as determined by SDS-PAGE.
          Formulation
          CHCHD3 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol and 2mM DTT.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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