CF-Blue - anti Mouse F4/80 - BM8

CF-Blue - anti Mouse F4/80 - BM8

Catalog Number:
A001109704IMM
Mfr. No.:
MOF4CFB(V25); MOF4CFB(V100)
Price:
$306
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      • Overview
        • F4/80 is a ~160 kDa transmembrane glycoprotein belonging to the EGF-TM7 family of G-protein-coupled receptors. F4/80 is considered a marker of choice for the identification of mature tissue macrophages, being broadly but variably expressed by this cell type in the liver (Kupffer cells), skin (Langerhans cells), bone marrow stroma, pancreas, thymus, spleen (red pulp), lung, and other tissues. It is also expressed by circulating monocytes, eosinophils and a subset of dendritic cells. F4/80 expression levels increase following activation of macrophages F4/80 is reportedly the only macrophage marker suitable for distinguishing destructive from non-destructive inflammatory processes in the pancreas.

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      • Properties
        • Host
          rat
          Isotype
          IgG2a
          Reactivity
          mouse
          Clone
          BM8
          Immunogen
          Murine macrophages
          Conjugate
          CF-Blue
          Storage
          Store in the dark at 2-8 °C
          Concentration
          0.5 mg/ml
          Molecular Weight
          19 kD
          Regulatory Status
          RUO
          Antigen
          EMR1, Ly71

          * For research use only.

      • Applications
        • Application
          Flow Cytometry

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