CD81 Mouse Monoclonal Antibody

CD81 Mouse Monoclonal Antibody

Catalog Number:
A001449406ZEN
Mfr. No.:
Zen-222517
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      • Overview
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          Background

          The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene.

      • Properties
        • Host
          mouse
          Isotype
          Mouse IgG1
          Reactivity
          human; rat
          Immunogen
          Purified recombinant fragment of human CD81 expressed in E. Coli.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Purified antibody in PBS with 0.05% sodium azide
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Molecular Weight
          Calculated MW: 26 kDa;Observed MW: 25-35 kDa
          Antigen
          (Gene ID:975; UniProt:P60033)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB; IHC-P; FC; ELISA
        • Application Dilutions
          WB 1/500-1/1000
          IHC 1/100-1/200
          FC 1/50-1/100
          ELISA 1/10000

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