CD284 Polyclonal Antibody

CD284 Polyclonal Antibody

Catalog Number:
A001507640RED
Mfr. No.:
RD230816A
Price:
$253
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      • Overview
        • Calculated MW: 96 kDa
          Observed MW: 95 kDa

          Please contact us at for specific academic pricing.

          Background

          The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Synthesized peptide derived from the Internal region of human CD284.
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          1 mg/mL
          Antigen
          ARMD10, CD284, CD284 antigen, Homolog of Drosophila toll, hToll, TLR 4, TLR4, TLR4, TOLL, Toll like receptor 4, Toll-like receptor 4 (UniProt:O00206)

          * For reference only.

      • Applications
        • Application
          WB; IHC-P; IF; ELISA
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:100-1:300
          IF 1:50-1:200
          ELISA 1:40000

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