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Overview
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Calculated MW: 61 kDa
Observed MW: 69 kDaPlease contact us at for specific academic pricing.
Background
CPB2 (Carboxypeptidase B2; also CPU and TAFI) is a secreted,50-60 kDa glycoprotein member of the peptidase M14 family of enzymes. It is expressed by hepatocytes (60 kDa) and platelets (50 kDa),with MW differences attributable to glycosylation. CPB2 is cleaved by thrombin and plasmin,generating a 36 kDa,relatively insoluble nonglycosylated enzymatically active fragment (TAFIa).
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