Name: Bulk anti-Human CD64 antibody - Low Endotoxin (10.1)
Price: 680.00 USD

- Overview
  - Antigen Distribution: FcγRI (CD64) is an IgG receptor expressed by monocytes and myeloid cell lines.
    Specificity: Clone 10.1 recognizes an epitope on human FcγRI
    Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
    Isotype Control: Mouse IgG1 Isotype Control for In Vivo - Low Endotoxin [HKSP] (ICH2247)
    Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
    Aggregation: Aggregation level ≤ 5%
    
    Please contact us at for specific academic pricing.
    
    Background
    
    Fc gamma receptors (FcγRs) are membrane-bound proteins which control and mediate communication of IgG antibodies within the immune system. These receptors play a crucial role in the link between the innate and adaptive immune system. FcγRI, CD64, is expressed on dendritic cells, macrophages/monocytes, and granulocytes. Of the FcγRs, FcγRI is capable of interacting with monomeric IgG with relatively high affinity.
- Properties
  - Host
    
    mouse
    
    Isotype
    
    IgG1 kappa
    
    Reactivity
    
    human
    
    Clone
    
    10.1
    
    Immunogen
    
    Rheumatoid synovial fluid cells and fibronectin purified human monocytes
    
    Purification
    
    >95% by SDS-PAGE and HPLC
    
    Formulation
    
    This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 – 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and azide free
    
    Storage
    
    This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
    
    Molecular Weight
    
    >2.0 mg/ml
    
    Regulatory Status
    
    Each investigator should determine their own optimal working dilution for specific applications.
    
    Antigen
    
    (Gene ID:Fc-gamma receptor 1, FcγRI, Fc Gamma Receptor Ia, Fc-Gamma RIA, CD64)
    
    * Products are for research use only. Not for use in diagnostic or therapeutic procedures.
- Applications
  - Application
    
    Blocking; Functional Assays; Flow Cytometry; Immunofluorescence; IHC (frozen); Immunoprecipitation

Bulk anti-Human CD64 antibody - Low Endotoxin (10.1)

Bulk anti-Human CD64 antibody - Low Endotoxin (10.1)

Background

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