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Overview
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Calculated MW: 47kDa/52kDa
Observed MW: 52kDaPlease contact us at for specific academic pricing.
Background
This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.
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