BRK1 Polyclonal Antibody

BRK1 Polyclonal Antibody

Catalog Number:
A001509719RED
Mfr. No.:
RD267071A
Price:
$347
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      • Overview
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          Background

          HSPC300 (hematopoietic stem cell protein 300) is also known as probable protein BRICK1 or C3orf10 (chromosome 3 open reading frame 10) and is a 75 amino acid protein that is expressed as two isoforms and localizes to both the cytoplasm and the cytoskeleton. HSPC300 is thought to regulate cytoskeletal organization and Actin polymerization. Free HSPC300 exists as homotrimers prior to its incorporation into the WAVE complex. The WAVE complex includes five proteins, one of which is HSPC300, that regulate the ARC (Arp2/3 complex) which is responsible for Actin nucleation and is Rac 1-dependent. Because HSPC300 is a highly conserved subunit of the WAVE complex across many species, it is thought to have the same or similar functions in many different organisms.

      • Properties
        • Host
          rabbit
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Recombinant fusion protein of human BRK1 (NP_060932.2).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          1 mg/mL
          Antigen
          BRK1, C3orf10, HSPC300, MDS027, hHBrk1 (Gene ID:55845; UniProt:Q8WUW1)

          * For reference only.

      • Applications
        • Application
          IHC; IF
        • Application Dilutions
          IHC 1:50-1:200
          IF 1:50-1:200

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