BLNK Polyclonal Antibody (1.02 mg/mL) for WB, IHC, ELISA

BLNK Polyclonal Antibody (1.02 mg/mL) for WB, IHC, ELISA

Catalog Number:
A001506659RED
Mfr. No.:
RD218540A
Price:
$253
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      • Overview
        • Calculated MW: 50 kDa
          Observed MW: Refer to figures
          Gene Accession: BC018906

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          Background

          This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Fusion protein of human BLNK
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          1.02 mg/mL
          Antigen
          AGM4, B cell adapter containing SH2 domain protein, B cell adapter containing Src homology 2 domain protein, B cell adaptor containing SH2 domain, B cell linker, B cell linker protein, B cell-specific adaptor protein, B-cell activation, B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, B-cell linker protein, BASH, Bca, BLNK, BLNK s, BLNK, Cytoplasmic adapter protein, Ly 57, Ly57, Lymphocyte antigen 57, Lyw 57, Lyw57, MGC111051, SH2 domain-containing leukocyte protein, 65-KD, SLP 65, SLP-65, SLP65, Src homology [SH2] domain-containing leukocyte protein of 65 kD, Src homology 2 domain containing leukocyte protein of 65 kDa, Src homology 2 domain-containing leukocyte protein of 65 kDa (UniProt:Q8WV28)

          * For reference only.

      • Applications
        • Application
          WB; IHC; ELISA
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:40-1:200
          ELISA 1:5000-1:10000

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