Biotin - anti Mouse CD90.2 - 30-H12

Biotin - anti Mouse CD90.2 - 30-H12

Catalog Number:
A001109452IMM
Mfr. No.:
MO902B(V500)
Price:
$439
  • Size:
    500 µg
    Quantity:
    Add to Cart:
      • Overview
        • CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymph ocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30-H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymph ocytes.

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      • Properties
        • Host
          rat
          Isotype
          IgG2b
          Reactivity
          mouse
          Clone
          30-H12
          Immunogen
          Mouse thymus or spleen
          Conjugate
          Biotin
          Storage
          Store in the dark at 2-8 °C
          Concentration
          0.5 mg/ml
          Molecular Weight
          25-35 kD
          Antigen
          Thy-1.2; T25; Thymus Cell Antigen 1; Theta

          * For research use only.

      • Applications
        • Application
          Flow Cytometry
          Application Description
          CD90.2, clone 30-H12, is a mAb intended for RUO in the identification of cells that express CD90.2. This reagent is effective for direct IF staining of mouse sample for FCM analysis using ≤1 µg/106 cells.

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