Name: BAIAP2L1 Polyclonal Antibody (0.7 mg/mL) for WB, IHC, ELISA
Price: 253.00 USD

Overview
- Calculated MW: 57 kDa
  Observed MW: Refer to figures
  Gene Accession: BC013888
  
  Please contact us at for specific academic pricing.
  
  Background
  
  This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Fusion protein of human BAIAP2L1
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  0.7 mg/mL
  
  Antigen
  
  BAI1 associated protein 2 like 1, BAI1 associated protein 2 like protein 1, BAI1-associated protein 2-like protein 1, Baiap2l1, BI2L1, Brain specific angiogenesis inhibitor 1 associated protein 2 like protein 1, Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1, FLJ42275, Insulin receptor tyrosine kinase substrate, IRTKS (UniProt:Q9UHR4)
  
  * For reference only.