Name: BAG3 Polyclonal Antibody (0.6 mg/mL) for WB, IHC, ELISA
Price: 253.00 USD

Overview
- Calculated MW: 62 kDa
  Observed MW: Refer to figures
  Gene Accession: BC014656
  
  Please contact us at for specific academic pricing.
  
  Background
  
  BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  Fusion protein of human BAG3
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  0.6 mg/mL
  
  Antigen
  
  BAG 3, BAG family molecular chaperone regulator 3, BAG-3, Bag3, BAG3, Bcl 2 binding protein, Bcl-2-associated athanogene 3, Bcl-2-binding protein Bis, BCL2 associated athanogene 3, BCL2 binding athanogene 3, BIS, CAIR 1, Docking protein CAIR 1, Docking protein CAIR-1, MFM6 (UniProt:O95817)
  
  * For reference only.

Applications

Application

WB; IHC; ELISA

Application	Dilutions
WB	1:500-1:2000
IHC	1:40-1:200
ELISA	1:5000-1:10000

BAG3 Polyclonal Antibody (0.6 mg/mL) for WB, IHC, ELISA

BAG3 Polyclonal Antibody (0.6 mg/mL) for WB, IHC, ELISA

Background

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