ATF6B Polyclonal Antibody (0.5 mg/mL) for WB, IHC, ELISA

ATF6B Polyclonal Antibody (0.5 mg/mL) for WB, IHC, ELISA

Catalog Number:
A001506569RED
Mfr. No.:
RD218330A
Price:
$253
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      • Overview
        • Calculated MW: 77 kDa
          Observed MW: Refer to figures
          Gene Accession: BC008394

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          Background

          The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Fusion protein of human ATF6B
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          0.5 mg/mL
          Antigen
          ATF6B, CREBL1, G13, Cyclic AMP-dependent transcription factor ATF-6 beta, cAMP-dependent transcription factor ATF-6 beta, Activating transcription factor 6 beta, ATF6-beta, Protein G13, cAMP response element-binding protein-related protein; (UniProt:Q99941)

          * For reference only.

      • Applications
        • Application
          WB; IHC; ELISA
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:25-1:100
          ELISA 1:5000-1:10000

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