Name: APP Polyclonal Antibody (1 mg/mL) for IF
Price: 416.00 USD

Overview
- Calculated MW: 8kDa/11kDa/12kDa/13kDa/16kDa/17kDa
  Observed MW: 17KDa
  
  Please contact us at for specific academic pricing.
  
  Background
  
  This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  A synthetic peptide of human APP
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% proclin300,50% glycerol,pH7.3.
  
  Storage
  
  Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
  
  Concentration
  
  1 mg/mL
  
  Antigen
  
  AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Amyloid beta A4, APP, Aβ42, preA4 (Gene ID:351; UniProt:P05067)
  
  * For reference only.

Applications

Application

IF

Application	Dilutions
IF	1:50-1:200

APP Polyclonal Antibody (1 mg/mL) for IF

APP Polyclonal Antibody (1 mg/mL) for IF

Background

We Also Recommend

CHRM1 Polyclonal Antibody (1 mg/mL) for WB

Ki67 Polyclonal Antibody (1 mg/mL) for IF

STAT3 Polyclonal Antibody (1 mg/mL) for WB, IF