Name: APOA1 Native Protein
Price: Inquiry

- Overview
  - Human HDL. APOA1 Human isolated from Human HDL is a single, glycosylated, polypeptide chain having a molecular mass of 28.3kDa. APOA1 is purified using delipidation and gel permeation chromatographic technique. APOA1 (Apolipoprotein A-1) is a human protein with a specific role in lipid metabolism being the main protein component of HDL in the plasma. APOA1 promotes cholesterol efflux from tissues to the liver for excretion. Furthermore, APOA1 is a cofactor for LCAT, which is responsible for the formation of most plasma cholesteryl esters. In addition, APOA1 activates spermatozoa motility as part of the SPAP complex. The APOA1 gene is strongly linked with two other apolipoprotein genes on chromosome 11. Defects in the APOA1 gene are linked to HDL deficiency including Tangier disease, and with systemic non-neuropathic amyloidosis. High levels of APOA1 are linked to the manifestation of asthma and atopy.
    
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- Properties
  - Protein Name
    
    Apolipoprotein A-I, Apo-AI, ApoA-I, APOA1, MGC117399.
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 95.0% as determined by SDS-PAGE.
    
    Formulation
    
    The APOA1 1mg/ml solution contains 10mM Ammonium Bicarbonate at pH7.4.
    
    Storage
    
    APOA1 although stable at 4°C for 1 week, should be stored below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

APOA1 Native Protein

APOA1 Native Protein

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