Anti-NBN antibody

Anti-NBN antibody

Catalog Number:
A001021827STJ
Mfr. No.:
STJ114898
Price:
$295
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      • Overview
        • Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Recombinant fusion protein containing a sequence corresponding to amino acids 435-754 of human NBN (NP_002476. 2).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Nibrin; Cell Cycle Regulatory Protein P95; Nijmegen Breakage Syndrome Protein 1 (Gene ID:4683; UniProt:O60934)

          * For research use only

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:1000

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