Name: Anti-Mouse IL-1a In Vivo Antibody - Low Endotoxin (ALF-161)
Price: 680.00 USD

- Overview
  - Specificity: Anti-IL-1a In Vivo Antibody - Low Endotoxin (ALF-161) recognizes Mouse IL-1A
    Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
    Isotype Control: Armenian Hamster IgG Isotype Control for In Vivo - Low Endotoxin [PIP] (ICH2251)
    Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
    Aggregation: Aggregation level ≤ 5%
    
    Please contact us at for specific academic pricing.
    
    Background
    
    Mouse IL-1alpha is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine.
- Properties
  - Host
    
    armenian hamster
    
    Isotype
    
    IgG1
    
    Reactivity
    
    mouse
    
    Clone
    
    ALF-161
    
    Purification
    
    >95% by SDS-PAGE and HPLC
    
    Formulation
    
    0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
    
    Storage
    
    anti-IL-1a In Vivo Antibody - Low Endotoxin (ALF-161) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
    
    Molecular Weight
    
    1.0 mg/ml
    
    Regulatory Status
    
    Each investigator should determine their own optimal working dilution for specific applications.
    
    Antigen
    
    (Gene ID:Interleukin-1 alpha, IL-1a)
    
    * Products are for research use only. Not for use in diagnostic or therapeutic procedures.
- Applications
  - Application
    
    WB; ELISA; ELISPOT; Neutralization; Immunoprecipitation; Flow Cytometry (intracellular)

Anti-Mouse IL-1a In Vivo Antibody - Low Endotoxin (ALF-161)

Anti-Mouse IL-1a In Vivo Antibody - Low Endotoxin (ALF-161)

Background

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