Anti-Mouse IFN gamma In Vivo Antibody - Low Endotoxin (XMG1.2)

Anti-Mouse IFN gamma In Vivo Antibody - Low Endotoxin (XMG1.2)

Catalog Number:
A001437288ICH
Mfr. No.:
ICH1141
Price:
$680
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      • Overview
        • Specificity: Anti-IFN gamma In Vivo Antibody - Low Endotoxin (XMG1.2) recognizes an epitope on Mouse IFN-gamma
          Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
          Isotype Control: Rat IgG1 Isotype Control for In Vivo - Low Endotoxin [GL113] (ICH2246)
          Endotoxin: <1.0 EU/mg as determined by the LAL method
          Aggregation: Aggregation level ≤ 5%

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          Background

          Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons. It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops. IFNG has antiviral, immunoregulatory, and anti-tumour properties.

      • Properties
        • Host
          rat
          Isotype
          IgG1
          Reactivity
          mouse
          Clone
          XMG1.2
          Immunogen
          Purified Recombinant Mouse IFN-gamma (>98%)
          Purification
          >95% by SDS-PAGE and analyzed by silver stain.
          Formulation
          0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
          Storage
          anti-IFN gamma In Vivo Antibody - Low Endotoxin (XMG1.2) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
          Molecular Weight
          1.0 mg/ml
          Regulatory Status
          Each investigator should determine their own optimal working dilution for specific applications.
          Antigen

          * Products are for research use only. Not for use in diagnostic or therapeutic procedures.

      • Applications
        • Application
          ELISA Capture; ELISPOT; IHC (frozen); Neutralization; WB; CyTOF

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