Anti-Mouse F4/80 Monoclonal Antibody ( PE/Cyanine7 Conjugated ) (0.2 mg/mL) for Flow Cytometry

Anti-Mouse F4/80 Monoclonal Antibody ( PE/Cyanine7 Conjugated ) (0.2 mg/mL) for Flow Cytometry

Catalog Number:
A001087660RED
Mfr. No.:
RD20138F
Price:
$268
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      • Overview
        • Please contact us at for specific academic pricing.

          Background

          F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+ T cells-mediated peripheral tolerance.

      • Properties
        • Host
          rat
          Antibody Type
          monoclonal
          Isotype
          IgG2b kappa
          Reactivity
          mouse
          Conjugate
          PE/Cyanine7
          Formulation
          PBS with 0.05% Proclin300, 1% BSA
          Storage
          Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
          Concentration
          0.2 mg/mL
          Antigen
          Adhesion G protein-coupled receptor E1; Adgre1; Cell surface glycoprotein F4/80; EGF-like module receptor 1; Adgre1; Emr1; Gpf480 (Gene ID:13733; UniProt:Q61549)

          * For research use only.

      • Applications
        • Application
          Flow Cytometry

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