Name: Anti-Mouse CD45R/B220 Monoclonal Antibody ( PE/Cyanine5 Conjugated ) (0.2 mg/mL) for Flow Cytometry
Price: 226.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    CD45, also known as leukocyte common antigen (LCA), B220, and T200, is a 180-2CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is eessed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.40 kD single chain type I membrane glycoprotein. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 is one of the best negative selection markers for characterizing and/or isolating human mesenchymal stem cells from bone marrow and other sources. s.
- Properties
  - Host
    
    rat
    
    Antibody Type
    
    monoclonal
    
    Isotype
    
    IgM
    
    Reactivity
    
    mouse
    
    Conjugate
    
    PE/Cyanine5
    
    Formulation
    
    PBS with 0.05% Proclin300, 1% BSA
    
    Storage
    
    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
    
    Concentration
    
    0.2 mg/mL
    
    Antigen
    
    B220; CD45; GP180; LCA; T200 (Gene ID:19264,5788; UniProt:P06800, P08575)
    
    * For research use only.
- Applications
  - Application
    
    Flow Cytometry

Anti-Mouse CD45R/B220 Monoclonal Antibody ( PE/Cyanine5 Conjugated ) (0.2 mg/mL) for Flow Cytometry

Anti-Mouse CD45R/B220 Monoclonal Antibody ( PE/Cyanine5 Conjugated ) (0.2 mg/mL) for Flow Cytometry

Background

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