Anti-Mouse CD150 Monoclonal Antibody ( PE Conjugated ) (0.2 mg/mL) for Flow Cytometry

Anti-Mouse CD150 Monoclonal Antibody ( PE Conjugated ) (0.2 mg/mL) for Flow Cytometry

Catalog Number:
A001087400RED
Mfr. No.:
RD21950F
Price:
$237
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      • Overview
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          Background

          CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.

      • Properties
        • Host
          rat
          Antibody Type
          monoclonal
          Isotype
          IgG2a lambda
          Reactivity
          mouse
          Conjugate
          PE
          Formulation
          PBS with 0.05% Proclin300, 1% BSA
          Storage
          Store at 2~8°C. Do not freeze.
          Concentration
          0.2 mg/mL
          Antigen
          Slam; Slamf1; CD 150; Signaling lymphocytic activation molecule (Gene ID:27218; UniProt:Q9QUM4)

          * For research use only.

      • Applications
        • Application
          Flow Cytometry

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