Name: Anti-Human CD8a-FITC/CD4-PE/CD3-PE/Cyanine7/CD45-PerCP Cocktail
Price: 374.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    This product is a FCM antibody cocktail made up of FITC Anti-Human CD8a Antibody [Clone: OKT-8] (Mouse IgG2a, κ), PE Anti-Human CD4 Antibody [Clone: RPA-T4] (Mouse IgG1, κ), PE/Cyanine7 Anti-Human CD3 Antibody [Clone: OKT-3] (Mouse IgG2a, κ) and PerCP Anti-Human CD45 Antibody [Clone: HI30] (Mouse IgG1, κ).;
    CD8 is mainly expressed on cytotoxic T cells and also some subpopulations of NK cells. CD8 forms dimer function. In most cells, CD8 is a heterodimer consisting of CD8a and CD8b, but in NK cells nearly all CD8 is homodimer of CD8a. CD8a can form co-receptor with MHC-I restricted TCR to promote T cell antigen recognition and activation.;
    CD4 is also called Leu-3 or T4. It's a single-chain type I transmembrane glycoprotein, mainly expressed on the surface of T cells, and monocytes/macrophages. In T cells, CD4 forms complex with TCR/CD3 and play important roles in T cell immunity. The target of HIV is CD4+ T cells. Reduction of CD4+ T cells is the main reason of defected immunity after HIV infection.;
    CD3 is a heterotetrameric protein consisting of a CD3γ, a CDδ and 2 CD3ε. It forms complex with TCR. OKT-3 recognize human CD3ε. Human CD3 is expressed on the surface of T cells and NKT cells.;
    CD45 is a single-chain type I transmembrane glycoprotein. Except for erythrocytes and platelets, CD45 is expressed on nearly all of the hematopoietic cells with high level. It is a common marker for blood leukocytes. CD45 is a receptor type protein tyrosine phophatase and plays essential roles in B cell and T cells signaling.
- Properties
  - Reactivity
    
    human
    
    Conjugate
    
    FITC; PE; PE/Cyanine7; PerCP
    
    Formulation
    
    Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
    
    Storage
    
    This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.
    
    Concentration
    
    5 μL/Test
    
    * For reference only.
- Applications
  - Application
    
    FCM

Anti-Human CD8a-FITC/CD4-PE/CD3-PE/Cyanine7/CD45-PerCP Cocktail

Anti-Human CD8a-FITC/CD4-PE/CD3-PE/Cyanine7/CD45-PerCP Cocktail

Background

We Also Recommend

Anti-Human CD19-FITC/CD56-PE/CD3-PE/Cyanine7/CD45-PerCP Cocktail

PE/AF594 Rat IgG2a, λ Isotype Control [G013C12] (0.2 mg/mL) for FCM

PE/AF594 Rat IgG2a, λ Isotype Control [G013C12] (5 μL/Test) for FCM