alpha 1 Fetoprotein Mouse Monoclonal Antibody

alpha 1 Fetoprotein Mouse Monoclonal Antibody

Catalog Number:
A001448651ZEN
Mfr. No.:
Zen-222031
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      • Overview
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          Background

          AFP (alpha-fetoprotein), a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

      • Properties
        • Host
          mouse
          Isotype
          Mouse IgG2b
          Reactivity
          human
          Immunogen
          Purified recombinant fragment of human AFP expressed in E. Coli.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Ascitic fluid containing 0.03% sodium azide.
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Molecular Weight
          Calculated MW: 69kDa;Observed MW: 69kDa
          Antigen
          (Gene ID:174; UniProt:P02771)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1/500-1/1000

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