Name: AKR1D1 cDNA
Price: 298.00 USD

- Overview
  - Aldo-keto reductase family 1, member D1, also known as AKR1D1, is a member of the AKR superfamily. The AKR family of proteins are soluble NADPH oxidoreductases. They play important roles in the metabolism of drugs, carcinogens and reactive aldehydes. AKR1D1 is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones which carry a delta (4) -3-one structure. AKR1D1 is highly expressed in liver, colon and testis. Deficiency of this enzyme may contribute to hepatic dysfunction.
    
    PRODUCT INFORMATION
    Antigen Species: Human
    NCBI Accession No: NP_005980.1
    RNA Reference Number: NM_005989.3
    OMIM Number: 604741
    Chromosome Location: 7q32-q33
    cDNA size: 981bp
    Vector description: This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    Aldo-keto reductase family 1 member D1, SRD5B1, Delta 4-3-ketosteroid-5-beta-reductase
    
    Type
    
    cDNAs
    
    Formulation
    
    Lyophilized
    
    Storage
    
    Store the plasmid at -20°C.
    
    Sequence
    
    Nucleotide Sequence: ATGGATCTCA GTGCTGCAAG TCACCGCATA CCTCTAAGTG ATGGAAACAG CATTCCCATC ATCGGACTTG GTACCTACTC AGAACCTAAA TCGACCCCTA AGGGAGCCTG TGCAACATCG GTGAAGGTTG CTATTGACAC AGGGTACCGA CATATTGATG GGGCCTACAT CTACCAAAAT GAACACGAAG TTGGGGAGGC CATCAGGGAG AAGATAGCAG AAGGAAAGGT GCGGAGGGAA GATATCTTCT ACTGTGGAAA GCTATGGGCT ACAAATCATG TCCCAGAGAT GGTCCGCCCA ACCCTGGAGA GGACACTCAG GGTCCTCCAG CTAGATTATG TGGATCTTTA CATCATTGAA GTACCCATGG CCTTTAAGCC AGGAGATGAA ATATACCCTA GAGATGAGAA TGGCAAATGG TTATATCACA AGTCAAATCT GTGTGCCACT TGGGAGGCGA TGGAAGCTTG CAAAGACGCT GGCTTGGTGA AATCCCTGGG AGTGTCCAAT TTTAACCGCA GGCAGCTGGA GCTCATCCTG AACAAGCCAG GACTCAAACA CAAGCCAGTC AGCAACCAGG TTGAGTGCCA TCCGTATTTC ACCCAGCCAA AACTCTTGAA ATTTTGCCAA CAACATGACA TTGTCATTAC TGCATATAGC CCTTTGGGGA CCAGTAGGAA TCCAATCTGG GTGAATGTTT CTTCTCCACC TTTGTTAAAG GATGCACTTC TAAACTCATT GGGGAAAAGG TACAATAAGA CAGCAGCTCA AATTGTTTTG CGTTTCAACA TCCAGCGAGG GGTGGTTGTC ATTCCTAAAA GCTTTAATCT TGAAAGGATC AAAGAAAATT TTCAGATCTT TGACTTTTCT CTCACTGAAG AAGAAATGAA GGACATTGAA GCCTTGAATA AAAATGTCCG CTTTGTAGAA TTGCTCATGT GGCGCGATCA TCCTGAATAC CCATTTCATG ATGAATACTG A
    Translation Sequence: MDLSAASHRI PLSDGNSIPI IGLGTYSEPK STPKGACATS VKVAIDTGYR HIDGAYIYQN EHEVGEAIRE KIAEGKVRRE DIFYCGKLWA TNHVPEMVRP TLERTLRVLQ LDYVDLYIIE VPMAFKPGDE IYPRDENGKW LYHKSNLCAT WEAMEACKDA GLVKSLGVSN FNRRQLELIL NKPGLKHKPV SNQVECHPYF TQPKLLKFCQ QHDIVITAYS PLGTSRNPIW VNVSSPPLLK DALLNSLGKR YNKTAAQIVL RFNIQRGVVV IPKSFNLERI KENFQIFDFS LTEEEMKDIE ALNKNVRFVE LLMWRDHPEY PFHDEY.
    
    * For research use only. Not intended for human, diagnostics or veterinary use.
- Applications
  - Application Description
    
    (1) Centrifuge at 7000rpm for 1 minute. (2) Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid.

AKR1D1 cDNA

AKR1D1 cDNA

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