AFViolet 450 Anti-Mouse Ly6A/E(Sca-1) Antibody [D7] (5 μL/Test) for FCM

AFViolet 450 Anti-Mouse Ly6A/E(Sca-1) Antibody [D7] (5 μL/Test) for FCM

Catalog Number:
A001514952RED
Mfr. No.:
RD30643F
Price:
$237
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      • Overview
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          Background

          Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

      • Properties
        • Host
          rat
          Isotype
          IgG2a kappa
          Reactivity
          mouse
          Conjugate
          AFViolet 450
          Formulation
          Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
          Storage
          This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.
          Concentration
          5 μL/Test
          Antigen
          Ly6a, Ly6, Ly-6A.2/Ly-6E.1, SCA-1, TAP, (Gene ID:110454)

          * For reference only.

      • Applications
        • Application
          FCM

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