AF647 Anti-Mouse CD150/SLAM Antibody [TC15-12F12.2] (0.5 mg/mL) for FCM

AF647 Anti-Mouse CD150/SLAM Antibody [TC15-12F12.2] (0.5 mg/mL) for FCM

Catalog Number:
A001514928RED
Mfr. No.:
RD30619F
Price:
$289
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      • Overview
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          Background

          CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.

      • Properties
        • Host
          rat
          Isotype
          IgG2a lambda
          Reactivity
          mouse
          Conjugate
          AF647
          Formulation
          Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
          Storage
          This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.
          Concentration
          0.5 mg/mL
          Antigen
          Slam, Slamf1, CD 150, Signaling lymphocytic activation molecule, (Gene ID:27218)

          * For reference only.

      • Applications
        • Application
          FCM

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